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pentobarbital will minimize the level or result of solifenacin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital raises toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. CYP3A4 inducers may increase the metabolism of ifosfamide to its active alkylating metab